DHP Hydroxyl gaw hpung hpe makawp maga na matu

3,4-Dihydro-2H-pyran (DHP, CAS 110-87-2) is a six-membered oxygen-containing heterocycle widely used in synthetic organic chemistry as a selective protecting reagent for alcohols. Acid hpe n-gun dat dat ai shaloi, DHP gaw hydroxyl lawm ai n-gun dat ni (ROH) hte loi loi sha shingdaw nna, tetrahydropyranyl (THP) ether ni hpe byin shangun ai majaw, hydroxyl hpung ni hpe npawt nhpang (sh) nucleophilic masa hta n-gun n rawng hkra galaw ya ai.

Ndai galai shai ai lam gaw tsi mawan ni, shingra tara arung arai ni, hte bungli galaw ai arung arai ni hpe multi-step synthesis galaw ai hta madung rai nna, lata la ai hku bai htang ai lam hpe ahkang jaw ai hte hkam sha lam ni hpe makawp maga ya ai. DHP- hpe madung tawn ai makawp maga lam gaw bai nhtang wa mai ai hte san seng ai-THP hpung ni hpe n-gun n rawng ai acidic hydrolysis npu hta asan sha garan nna, n-gun n rawng ai alcohol hpe bai gram lajang lu ai.

Arung arai mying	DHP gaw Hydroxyl hpung hpe makawp maga na matu
CAS NO.	110-87-2
Ga si bung ai	DHP
Molecular hkrang masa	C5H8O
HS Tara	2932999099
Hkrang masa

(Synthetic Chemistry hta Hydroxyl hpe n-gup magap galaw na matu ahkyak ai Reagent langai)

• THP Ether byin pru wa ai hku nna Hydroxyl hpung hpe makawp maga ai lam:

Acid (ga shadawn, p-TsOH, HCl) nga ai shara hta DHP gaw alcohol ni hte shingdaw nna THP ether ni hpe byin shangun ai.

Ndai makawp maga hpung gaw hydroxyl hpung ni hpe shabyin ya ai .-n ​​htang n galaw ainpawt nhpang, oxidant, hte n-gun dat ni hpe garan jaw ai.

THP ether ni gaw .npawt nhpang hte nucleophilic masa ni hta ngang grin ai, shanhte hpe yak hkak ai synthesis bungli galaw ai lam ni a matu kaja dik htum byin shangun ai.

• N-gun n rawng ai makawp maga lam:

THP hpung hpe n-gun n rawng ai hka n-gun (ga shadawn, 1% HCl (sh) acetic acid) hte loi loi hte shapraw kau lu nna, npawt nhpang hydroxyl hpung hpe sadi dung ai lam kaba hte bai gram lajang ya lu ai.

Grai sawng ai masa ni (sh) laksan reagents ni n ra ai.

• Multistep Hkrang Shachyaw ai hta jai lang mai ai lam ni:

Tsi hpaji hpe hpawng de ai: ga shadawn, steroids, ana zinli hpe sat ai tsi ni, ana zinli hpe sat ai tsi ni

Peptide hte amino tsa chyaru tsi hpaji

Carbohydrate hpe makawp maga ya ai: Sugar ni hta lata la ai hydroxyl hpe shingdang da ai

Shingra tara arung arai yawng hpe hpawng de ai

• Tsi mawan lapran na alcohol ni hpe makawp maga ai
• THP-makawp maga da ai tsa chyaru ni hpe tsi mawan galaw shapraw na matu hpawng de ai
• Hkrak ai shingra tara n-gun dat ni hpe yawng hpawng de ai
• Kaja ai tsi mawan ni hte laksan arung arai ni a tsi hpaji
• Peptide maga de na sumri hte carbohydrate hydroxyl makawp maga ai lam