Tsi hpaji lapran na 3,4-dihydro-2H-pyran

3,4-Dihydro-2H-pyran (DHP, CAS 110-87-2) gaw, tsi mawan n-gun rawng ai tsi mawan (API) hpe hpaw shapraw ai hta grai lang ai ahkyak ai tsi mawan langai rai nga ai. Ndai 6 lawm ai heterocyclic ether gaw, tetrahydropyranyl (THP) ether ni hpe hpaw shabawn ai hku nna, hydroxyl hpung ni hpe makawp maga ya ai ahkyak ai magam bungli hpe galaw ya nga ai. Shi a atsam gaw, n-gun n rawng ai acid npu hta alcohol a bungli ni hpe makoi magap da lu nna, aqueous acid npu hta san seng ai hku bai nhtang wa lu ai majaw, multistep drug synthesis hta ahkyak dik htum rai nga ai.

Dihydropyran (sh) biomass- kaw na lu la ai furfural hpe hydrogen galaw ai hku nna galaw shapraw ai DHP gaw, hkai sun hkai sun npawt tara ni hte maren rai nga ai. Shi a makawp maga ai reagent hte reactive lapran na lit lahkawng gaw, kaga manu dan ai API ni hta, corticosteroids, macrolide antibiotics, hte HIV protease hpe pat shingdang ai tsi ni hpe galaw shapraw ai hta shi a manu hpe ngang kang shangun ai.

Arung arai mying	3,4-Dihkaidro-2H-pyran
CAS NO.	110-87-2
Ga si bung ai	DHP
Molecular hkrang masa	C5H8O
HS Tara	2932999099
Hkrang masa

• API hpe galaw ai hta Hydroxyl hpe makawp maga ai lam:

DHP hpe THP ethers hku nna, nanghpam tsi mawan lapran na alcohol hpung ni hpe lata nna makawp maga na matu lang ai. Ndai hpung ni gaw basic hte nucleophilic masa hta ngang grin nga ai rai nna, dilute acid ni hpe lang nna san seng ai hku shapraw kau mai ai.

• Lahkam law law na Organic hpawng chyawm ai lam:

Alcohol-lawm ai lapran na arung arai ni gaw, maga mi de n-gun n rawng ai sha, matut nna bungli galaw ra ai synthesis lam ni hpe loi lajang ya ai.

• Tsi mawan ni hpe galaw shapraw ai hta ahkyak ai jai lang ai lam ni:

Erythromycin (makrolid ana zinli hpe sat ai tsi):DHP hpe ring byin ai shaloi lata la ai hydroxyl makawp maga na matu lang ai.

Kortikosteroid tsi ni:Hkrak ai ring bai gram lajang ai lam ni hte oxidation lahkam ni hta hydroxyl hpung ni hpe makawp maga ya ai.

HIV hpe pat shingdang ai tsi ni:Peptomimetic tsi ni hta, DHP gaw hka lim ai hte hka lim ai aten hta maga na shingnip ni hpe ngang grin hkra galaw ya ai.

• Hpun kawa hpaji lapran tsang:

Furfural-a kaw na lu la mai ai, biomass-madung tawn ai tsi mawan-DHP hpe tsi mawan lang na matu ngang grin ai lapran lam langai hku nna tawn da ai.

180 kg hka htung (law law), 1L/5L gawm (laboratory (sh) pilot scale) hta pat da ai.